Spencer,astrugglingcomedianandhypochondriac,isconvincedthathe'sdyingfromabizarrearrayofsymptoms.OutofoptionsandarmedwithabinderfullofWebMDprintouts,hefliescross-countrytohisquainthometowninupstateNewYorktoconsultwithhisfivechildhooddoctorsinasingleday,planningtotakethered-eyebacktoL.A.thatnightwithoutseeinganyofhisfriendsorfamily.TheonlyexceptionisJay-thesweet,emotionallyrepressedtownieSpencerconvincestochauffeurhimaround."5Doctors"isthestoryoftheirincreasinglydisastrousdaytogether,asSpencerisprodded,dilated,andbiopsiedintoacceptingthatthecauseofhissymptomsandhisreasonsforcominghomemaybemorecomplicatedthanhethought.